The American Journal of Digestive Diseases

, Volume 21, Issue 10, pp 895–900 | Cite as

Fulminant hepatic failure secondary to congestive heart failure

  • Barry Kisloff
  • Gerald Schaffer
Case Report


An elderly female with an acute episode of congestive heart failure, unaccompanied by any periods of hypotension, developed fulminant hepatic failure with an accompanying coagulopathy. Attempts to establish an etiology for her acute hepatic insufficiency, other than cardiac failure, proved negative. Fulminant hepatic failure as a consequence of congestive heart failure, without prolonged periods of hypotension preceding alteration in hepatic function, has not heretofore been described. Liver function is adversely effected in congestive heart failure. Hepatic ammonia clearance is impaired in cardiac failure and may be diminished to the point of resulting in hepatic encephalopathy. Coagulopathy is a frequent concomitant of fulminant hepatic failure. Establishing a clear etiology for a coagulopathy in the face of concomitant liver disease is difficult, thus making any therapeutic intervention fraught with peril.


Ammonia Liver Disease Congestive Heart Failure Liver Function Therapeutic Intervention 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Digestive Disease Systems, Inc. 1976

Authors and Affiliations

  • Barry Kisloff
    • 1
  • Gerald Schaffer
    • 1
  1. 1.Division of Gastroenterology, Department of MedicineMedical College of VirginiaRichmond

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