A very easily performed new technique of simultaneous introduction of Rubin's multipurpose biopsy tube and gastrofiberscope in the diagnosis of reflux esophagitis is described. This technique will obviate the need of taking multiple biopsies and adds the advantage of direct observation of abnormal mucosa. As the biopsy is obtained under direct vision, there is no need of x-ray or manometric localization and one can avoid inadvertently biopsying a varix or a friable ulcer
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Hootkin LA, Benz LJ, Margulies S, Cauthorne RT, Hendrix TR: A comparison of clinical measurements of gastroesophageal reflux. Gastroenterology 58:1044, 1970
Ismail-Beigi F, Horton PF, Pope CE II: Histologic consequences of gastroesophageal reflux in man. Gastroenterology 58:163–174, 1970
Ismail-Beigi F, Pope CE II: Distribution of the histological changes of gastroesophageal reflux in the distal esophagus of man. Gastroenterology 66:1109–1113, 1974
Brandborg LL, Rubin CE, Quinton EQ: A multipurpose instrument for suction biopsy of the esophagus, stomach, small bowel and colon. Gastroenterology 37:1–16, 1959
Quinton WE, Flick AL, Rubin CE: The design of a hydraulic suction tube for peroral biopsy of the human gastrointestinal tract. Gastroenterology 42:281–284, 1962
Mangla JC: Endoscopic diagnosis of Barrett's esophagus. Unpublished manuscript
Mangla JC, Kim YM, Guarasci G, et al: Pepsinogens in epithelium of Barrett's esophagus. Gastroenterology 65:949–955, 1973
Vidinli M, Finlay JM: Massive hemorrhage following small bowel biopsy. Can Med Assoc J 91:1223, 1964
Dobbins WO III, Trier JS, Parkins WC et al: A warning regarding the dangers of hydraulic biopsy in gastrointestingal research. Gastroenterology 45:335–340, 1963
McDonald WG: Perforation and hemorrhage after gastrointestinal mucosal biopsy in a child. Gastroenterology 51:390–392, 1966
Roesch W: Gastro-esophageal reflux and hiatus hernia—endoscopy. Postgrad Med J 50:199–201, 1974
About this article
Cite this article
Mangla, J.C., Kalra, T.M. A new technique of endoscopic esophageal biopsy using multipurpose biopsy tube in the diagnosis of reflux esophagitis. Digest Dis Sci 20, 775–780 (1975). https://doi.org/10.1007/BF01070836
- Public Health
- Direct Observation
- Direct Vision
- Reflux Esophagitis