Behavior Genetics

, Volume 8, Issue 1, pp 3–13

Response to 30 generations of selection for open-field activity in laboratory mice

  • J. C. DeFries
  • Mary Cook Gervais
  • E. A. Thomas
Article

DOI: 10.1007/BF01067700

Cite this article as:
DeFries, J.C., Gervais, M.C. & Thomas, E.A. Behav Genet (1978) 8: 3. doi:10.1007/BF01067700

Abstract

High and low lines resulting from 30 generations of bidirectional selection for open-field activity have nonoverlapping distributions and more than a thirtyfold difference in mean activity. Open-field defecation scores of lowactive lines are approximately 7 times higher than those of high-active lines, substantiating earlier reports of a large, negative genetic correlation between these characters. Since the selection experiment is replicated, other variables which are found to be reliably different among the high, control, and low lines are likely to be causally related to open-field activity; thus these selected lines of mice may be of use to other investigators.

Key Words

open-field behavior selection mice activity albinism 

Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • J. C. DeFries
    • 1
  • Mary Cook Gervais
    • 1
  • E. A. Thomas
    • 1
  1. 1.Institute for Behavioral GeneticsUniversity of ColoradoBoulder

Personalised recommendations