Behavior Genetics

, Volume 10, Issue 1, pp 31–41 | Cite as

Language and cognitive development in 47, XXX females followed since birth

  • B. Pennington
  • M. Puck
  • A. Robinson
Article

Abstract

In this report, data are presented on language and cognitive development in an unselected group of eleven 47, XXX females, followed since birth, who are now 6–14 years old. The results of the Yale Developmental Exam (at 2 years) and the Illinois Test of Psycholinguistic Abilities (ITPA) (at 4–6 years) show an early delay in language development. Those girls who presently have serious language and learning problems were significantly delayed in first walking or talking, whereas the relatively unaffected girls were not. Results of the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) at 4 years of age and the Wechsler Intelligence Scale for Children (WISC or WISC-R) at 8 years of age are similar and show a generalized depression of both verbal and nonverbal abilities. Thus, unlike 45, X females or 47, XXY males, triple-X females do not have a specifically nonverbal or verbal cognitive deficit.

Key Words

47, XXX 45, X sex chromosome aneuploidy cognitive development language development learning disabilities WPPSI WISC WISC-R ITPA YDE psycholinguistics 

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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • B. Pennington
    • 1
  • M. Puck
    • 1
  • A. Robinson
    • 1
  1. 1.National Jewish Hospital and Research Center/National Asthma Center and University of Colorado Health Sciences CenterDenver

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