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Selective breeding for acoustic priming

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Data on eight generations of selective breeding for acoustic priming efficacy are reported. The realized heritability of this trait is approximately 0.2–0.3, indicating that the trait is determined in part by genetic factors. Animals selectively bred for acoustic priming do not differ in terms of first-trial (i.e., non-priming-induced) audiogenic seizures. These data suggest that acoustic priming and first-trial audiogenic seizures are controlled by different genetic mechanisms.

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This research was supported by Research Grant MH 13026 from the National Institute of Mental Health.

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Deckard, B.S., Tepper, J.M. & Schlesinger, K. Selective breeding for acoustic priming. Behav Genet 6, 375–383 (1976). https://doi.org/10.1007/BF01065695

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Key Words

  • audiogenic seizures
  • mice
  • acoustic priming
  • genetics