Neurophysiology

, Volume 11, Issue 2, pp 92–96 | Cite as

Neurons of the thalamic ventrobasal complex, labeled with horseradish peroxidase, projecting to the primary somatosensory cortex in cats

  • V. Yu. Ermolaeva
  • V. P. Babmindra
  • N. A. Brukhanskaya
Article
  • 19 Downloads

Abstract

The morphology and localization of neurons of the thalamic ventrobasal complex projecting to the primary somatosensory cortex were studied in cats by the retrograde axonal transport of exogenous horseradish peroxidase method. Different types of neurons were detected: triangular, round with symmetrical processes, oval with processes diverging asymmetrically, and fusiform. Tagged neurons were distributed as two large populations in the central region of the complex adjoining the boundaries of the two nuclei. Comparison with the somatotopic map showed that the tagged neurons were concentrated mainly in the projection area of the forelimb and head. Since microinjections of peroxidase into the somatosensory cortex also were given in the projection areas for the forelimb and head, the results confirm the neurophysiological concept of strict somatotopic organization of thalamocortical input.

Keywords

Central Region Large Population Horseradish Peroxidase Projection Area Axonal Transport 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    V. Yu. Ermolaeva, "Morphology of connections of the thalamic ventrobasal complex with the first and second somatosensory areas of the cortex," Dokl. Akad. Nauk SSSR,198, 716 (1971).Google Scholar
  2. 2.
    V. M. Storozhuk, Functional Organization of Neurons of the Somatic Cortex [in Russian], Kiev, Naukova Dumka (1974), 269 pp.Google Scholar
  3. 3.
    H. Akimoto, K. Nogishi, and K. Yamada, "Studies of thalamo-cortical connections in cats by means of retrograde degeneration methods," Folia Psychiat. Neurol. Jpn.,10, 39 (1956).Google Scholar
  4. 4.
    P. Andersen, J. C. Eccles, and T. A. Sears, "The ventro-basal complex of the thalamus: Types of cells, their responses and their functional organization," J. Physiol. (London),174, No. 3 370 (1964).Google Scholar
  5. 5.
    P. Andersen, S. A. Andersen, and T. Lomo, "Nature of thalamo-cortical relations during spontaneous barbiturate spindle activity," J. Physiol. (London),192, 283 (1967).Google Scholar
  6. 6.
    R. C. Graham, Jr., and M. J. Karnovsky, "The early stages of absorption of injected horseradish peroxidase in the proximal tubules of the mouse kidney; ultrastructural cytochemistry by a new technique," J. Histochem. Cytochem.,14, 291 (1966).Google Scholar
  7. 7.
    H. H. Jasper and C. Ajmone-Marsan, A Stereotaxic Atlas of the Diencephalon of the Cat, Ottawa (1954).Google Scholar
  8. 8.
    E. G. Jones and T.P.S. Powell, "The cortical projection of the ventroposterior nucleus of the thalamus in the cat," Brain Res.,13, 298 (1969).Google Scholar
  9. 9.
    E. G. Jones and R.Y. Leavitt, "Demonstration of thalamocortical connectivity in the cat somatosensory system by retrograde axonal transport of horseradish peroxidase," Brain Res.,63, 414 (1973).Google Scholar
  10. 10.
    J. Kievit and H. G. J. M. Kuypers, "Subcortical afferents to the frontal lobe in rhesus monkey studied by means of retrograde horseradish peroxidase transport," Brain Res.,85, 261 (1975).Google Scholar
  11. 11.
    J. Kievit and H. G. J. M. Kuypers, "organization of the thalamocortical connexions to the frontal lobe in the rhesus moneky," Exp. Brain Res.,29, 299 (1977).Google Scholar
  12. 12.
    S. H. La Vail and M. M. La Vail, "The retrograde transport of horseradish peroxidase in the chick visual system. A light and electron microscopic study," J. Comp. Neurol.,157, 303 (1974).Google Scholar
  13. 13.
    G. Macchi, F. Angeleri, and G. Guazzi, "Thalamo-cortical connections of the first and second somatic sensory areas in the cat," J. Comp. Neurol.,111, 387 (1959).Google Scholar
  14. 14.
    J. Manson, "The somatosensory cortical projection of single cells in the thalamus of the cat," Brain Res.,12, 489 (1969).Google Scholar
  15. 15.
    M. M. Mesulam, "The blue reaction product in horseradish peroxidase neurohistochemistry: incubation parameters and visibility," J. Histochem. Cytochem.,24, 1273 (1976).Google Scholar
  16. 16.
    V. Mountcastle and E. Henneman, "The pattern of tactile representation in thalamus of cat," J. Neurophysiol.,12, 85 (1949).Google Scholar
  17. 17.
    H. J. Ralston and P. V. Sharp., "The identification of the thalamocortical relay cells in the adult cat by means of retrograde axonal transport of horseradish peroxidase," Brain Res.,62, 273 (1973).Google Scholar
  18. 18.
    J. E. Rose and V. Mountcastle, "The thalamic tactile region in rabbit and cat," J. Comp. Neurol.,97, 441 (1952).Google Scholar
  19. 19.
    M. Scheibel and A. Scheibel, "Patterns of organization in specific and nonspecific thalamic fields," in: The Thalamus, Columbia University Press, New York (1967), pp. 13–46.Google Scholar
  20. 20.
    T. Tombol, "Short neurons and their synaptic relations in the specific thalamic nuclei," Brain Res.,3, 307 (1966/67).Google Scholar
  21. 21.
    H. Vanegas, H. Hollander, and H. Distel, "Early stages of uptake and transport of horseradish peroxidase by cortical structures and its use for the study of local neurons and their processes," J. Comp. Neurol.,177, 193 (1978).Google Scholar
  22. 22.
    C. N. Woolsey, "Organization of somatic sensory and motor areas of the cerebral cortex," in: Biological and Biochemical Bases of Behavior, University of Wisconsin Press, Madison (1958), pp. 63–81.Google Scholar

Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • V. Yu. Ermolaeva
  • V. P. Babmindra
  • N. A. Brukhanskaya

There are no affiliations available

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