We recorded the activity of two types of granular cells in the rostral folia of the paramedial lobe (the projection region of the front legs) of the cerebellar cortex in cats immobilized by administration of ditiline; these cells differed in their receptive fields, the characteristics of their reaction to single stimulation of somatic nerves, and the character of their background activity. The granular cells of the first type were excited only when the nerves of the front legs were stimulated (reacting with 1–3 impulses with a latent period of 8–20 msec) and were inhibited between 20–50 and 70–180 msec after stimulation of the nerves of any leg. The cells of the second type responded with volleys of 3–6 impulses with a latent period of 20–40 msec to stimulation of the nerves of all four legs. Comparison of the reactions of the granular cells and other neurons of the cerebellar cortex showed that the cells of the first type cause excitation of the Purkinje and Golgi cells and the neurons of the molecular layer. The granular cells of the second type have an excitatory effect on the Golgi cells. The differences in the reactions of the two types of granular cells result from the fact that they are selectively innervated by the mossy fibers of different afferent pathways. Comparison with the data in the literature enables us to surmise that the fibers of the cuneocerebellar tract terminate at granular cells of the first type, while the reticular fibers terminate at cells of the second type.
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Yu. I. Arshavskii, M. B. Berkinblit, I. M. Gel'fand, and V. S. Yakobson, "Functional organization of the afferent pathways of the Purkinje cells of the cerebellar paramedial lobe," Dokl. Akad. Nauk SSSR,177, 732–735 (1967).
Yu. I. Arshavskii, M. B. Berkinblit, I. M. Gel'fand, and V. S. Yakobson, "Analysis of the reactions of single neurons and their interaction in the cerebellar cortex on stimulation of peripheral nerves," Proceedings of a Symposium on the Structural and Functional Organization of the Cerebellum [in Russian], Erevan (1968), pp. 17–19.
Yu. I. Arshavskii, M. B. Berkinblit, and O. I. Fukson, "Layer by layer analysis of the evoked potentials of the paramedial lobe of the cerebellar cortex," Fiziol. Zh. SSSR,55, 429–437 (1969).
V. V. Smolyaninov, "Certain characteristics of the organization of the cerebellar cortex," in: Models of the Structural-Functional Organization of Certain Biological Systems [in Russian], Nauka, Moscow (1966), pp. 203–262.
E. C. Crichlow and T. T. Kennedy, "Functional characteristics of neurons in the lateral reticular nucleus with reference to localized cerebellar potentials," Exptl. Neurol.,18, 141–153 (1967).
J. E. Eccles, M. Ito, and J. Szentagothai, the Cerebellum as a Neuronal Machine, Berlin (1967).
G. Grant, "Projection of the external cuneate nucleus onto the cerebellum in the cat. An experimental study using silver methods," Exptl. Neurol.,5, 179–195 (1962).
B. Holmqvist, O. Oscarsson, and I. Rosen, "Functional organization of the cuneocerebellar tract in the cat," Acta. Physiol. Scand.,59, 216–235 (1963).
Y. Laporte, A. Lundberg, and O. Oscarsson, "Functional organization of the dorsal spinocerebellar tract in the cat. II. Single fibre recording in Elechsig's fasciculus," Acta. Physiol. Scand.,36, 188–203 (1956).
A. Lundberg and O. Oscarsson, "Functional organization of the dorsal spinocerebellar tract in the cat. VII. Identification of units by antidromic activation from the cerebellar cortex with recognition of five functional subdivisions," Acta Physiol. Scand.,50, 356–374 (1960).
I. McCance and J. W. Phillis, "Cholinergic mechanisms in the cerebellar cortex," Intern. J. Neuropharmacol.,7, 447–462 (1968).
O. Oscarsson, "Functional significance of information channels from the spinal cord to the cerebellum," in: Neurophysiological Basis of Normal and Abnormal Motor Activities, New York (1967), pp. 93–117.
O. Oscarsson and I. Rosen, "Response characteristics of reticulocerebellar neurons activated from spinal afferents," Exptl. Brain. Res.,1, 320–328 (1966).
R. C. Thomas and V. J. Wilson, "Marking single neurons by staining with intracellular recording microelectrodes," Science,151, 1538–1539 (1966).
Institute of Problems of Information Transmission, Academy of Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 1, No. 2, pp. 167–176, September–October, 1969.
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Arshavskii, Y.I., Berkinblit, M.B., Gel'fand, I.M. et al. Two types of granular cells in the cerebellar cortex. Neurophysiology 1, 128–134 (1969). https://doi.org/10.1007/BF01063182
- Latent Period
- Receptive Field
- Molecular Layer
- Cerebellar Cortex
- Background Activity