Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Activation of the nuclei of Goll and Burdach in the medulla oblongata by visceral afferent systems

  • 19 Accesses

Abstract

Projections of the mesenteric and pelvic nerves in the nuclei of Goll and Burdach were studied by the evoked potentials method in cats anesthetized with chloralose and immobilized with listhenon. Stimulation of visceral nerves is accompanied by the development of biphasic potentials with an initial positive wave. Potentials were recorded in all parts of the nuclei studied. The latent periods of responses to stimulation of the mesenteric nerves varied from 13 to 22 msec, and to stimulation of the pelvic nerves from 8 to 21 msec. Potentials appeared later in the nucleus of Burdach in response to stimulation of the same nerves. The amplitudes of the responses depended on the location of the recording electrode. The features of organization of projections of these visceral nerves suggest the existence of special nuclear formations for projections of visceral nerves in the medulla similar to the para-alar nucleus for the pelvic nerves.

This is a preview of subscription content, log in to check access.

Literature cited

  1. 1.

    A. M. Blinova, N. K. Saradzhaev, and F. D. Sheikhon, "Unit activity of bulbar pressor structures in reflexes from the urinary bladder mechanoreceptors and afferent fibers of the tibial nerve," Byull. Éksperim. Biol. i Med.,62, 8–12 (1966).

  2. 2.

    A. A. Grantyn', "Morphology, topography, and connections of the medulla and pons of the cat," Current Problems in Pharmacology of the Reticular Formation and Synaptic Transmission [in Russian], First Edition, Leningrad Medical Institute, Leningrad (1963), pp. 165–190.

  3. 3.

    R. A. Durinyan, The Central Structure of Afferent Systems [in Russian], Nauka, Leningrad (1965).

  4. 4.

    G. I. Kozlova, "Structural features of synaptic endings in the nucleus of Burdach," Dokl. Akad. Nauk SSSR,49, 189 (1963).

  5. 5.

    P. G. Kostyuk, Yu. P. Limanskii, N. N. Preobrazhenskii, and Z. A. Tamarova, "Convergence of somatic and visceral influences on spinal and reticular neurons," Integrative Activity of the Nervous System under Normal and Pathological Conditions [in Russian], Meditsina, Moscow (1968), pp. 5–20.

  6. 6.

    K. M. Kullanda, "Comparative characteristics of zones of representation of the pelvic and pudendal nerves in the cerebral cortex of cats and dogs," Fiziol. Zh. SSSR,46, 1336 (1960).

  7. 7.

    O. S. Merkulova and T. V. Popov, "Changes in bioelectrical activity of the medulla during stimulation of urinary bladder receptors," Fiziol. Zh. SSSR,53, 280 (1967).

  8. 8.

    S. S. Musyashchikova, "Afferent visceral representation in the central nervous system," Mechanisms of Regulation of Physiological Functions [in Russian], Nauka, Leningrad (1971), pp. 258–277.

  9. 9.

    O. A. Nikitin, "Some properties of ventral root responses to stimulation of the pelvic nerve and somatic nerves of the cat," Fiziol. Zh. SSSR,59, 1699 (1973).

  10. 10.

    N. N. Preobrazhenskii and Yu. P. Limanskii, "Activation of reticular neurons of the medulla by visceral afferents," Neirofiziologiya,1, 177 (1969).

  11. 11.

    V. S. Raitses and A. A. Shlyakhovenko, "On the functional organization of the visceral and somatic afferent connections of the vestibular nuclei," Fiziol. Zh. SSSR,58, 377 (1972).

  12. 12.

    V. N. Chernigovskii and S. M. Zaraiskaya, "Representation of the vagus nerve in the cerebral cortex and the limbic lobe of the cat brain," Dokl. Akad. Nauk SSSR,47, 742 (1962).

  13. 13.

    O. Aidar, W. A. Geohegan, and L. N. Undewitter, "Splanchnic afferent pathways in the central nervous system," J. Neurophysiol.,15, 131 (1952).

  14. 14.

    V. E. Amassian, "Cortical representation of spinal pathways of visceral afferents," Fed. Proc.,9, 5 (1950).

  15. 15.

    V. E. Amassian, "Cortical representation of visceral afferents," J. Neurophysiol.,14, 433 (1951).

  16. 16.

    P. Anderson, J. C. Eccles, R. F. Schmidt, and T. Yokata, "Identification of relay cells and interneurons in the cuneate nucleus," J. Neurophysiol.,27, 1080 (1964).

  17. 17.

    M. A. Biedenbach, "Cell density and regional distribution of cell types in the cuneate nucleus of the rhesus monkey," Brain Res.,45, 1 (1972).

  18. 18.

    D. Bowsher, "Projection of the gracile and cuneate nuclei inMacaca mulatta: an experimental degeneration study," J. Comp. Neurol.,110, 135 (1958).

  19. 19.

    S. Ramon y Cajal, Histologie du Systeme Nerveux de l'Homme et des Vertebres, Vol. 2, Paris, Maloine (1911), p. 993.

  20. 20.

    C. B. B. Downman, "Cerebral destination of splanchnic afferent impulses," J. Physiol. (London),113, 434 (1951).

  21. 21.

    C. B. B. Downman and M. N. Evans, "The distribution of splanchnic afferents in the spinal cord of cat," J. Physiol. (London),131, 66 (1957).

  22. 22.

    G. Gordon and M. G. M. Jukes, "Dual organization of the exteroceptive components of the cat's gracile nucleus," J. Physiol. (London),173, 263 (1964).

  23. 23.

    G. Gordon and M. G. M. Jukes, "Correlation of different excitatory and inhibitory influences on cells in the nucleus gracilis of the cat," Nature,196, 1183 (1962).

  24. 24.

    G. Gordon and C. Paine, "Some features of the physiological organization of nucleus gracilis in the cat," J. Physiol. (London),148, 34 (1959).

  25. 25.

    F. H. Johnson, "Microelectrode studies on the cuneate and gracile nuclei of the cat," Amer. J. Physiol.,171, 737 (1952).

  26. 26.

    J. H. Keller and P. J. Hand, "Dorsal root projections of the nucleus cuneatus of the cat," Brain Res.,20, 1 (1970).

  27. 27.

    L. H. Kruger, R. Siminoff, and P. Witkovsky, "Single neuron analysis of dorsal column nuclei and spinal nucleus of trigeminal in cat," J. Neurophysiol.,24, 333 (1961).

  28. 28.

    M. Kuru, "Nervous control of micturition," Physiol. Rev.,45, 425 (1965).

  29. 29.

    H. G. J. Kuypers, A. L. Hoffman, and R. M. Beasley, "Distribution of feed-back cortical fibers in the nucleus cuneatus and gracilis," Proc. Soc. Exp. Biol. (New York),108, 634 (1961).

  30. 30.

    J. G. McLeod, "Splanchnic representation in the thalamus of the cat," J. Physiol. (London),140, 462 (1958).

  31. 31.

    P. P. Newman, "Potential changes in the parietal cortex on stimulation of the splanchnic nerve," J. Physiol. (London),116, 8 (1952).

  32. 32.

    J. Rozsos, "The synapses of Burdach's nucleus," Acta Morph. Acad. Sci. Hung.,8, 105 (1958).

  33. 33.

    E. Taber, "The cytoarchitecture of the brain stem of the cat," J. Comp. Neurol.,116, 27 (1961).

  34. 34.

    A. Taub and P. O. Bishop, ‘The spino-cervical tract: dorsal column linkage, conduction velocity, primary afferent spectrum," Exp. Neurol.,13, 1 (1965).

  35. 35.

    P. O. Therman, "Transmission of impulses through the Burdach nucleus," J. Neurophysiol.,2, 154 (1941).

  36. 36.

    K. C. Tomasulo and R. Emmers, "Activation of neurons in the gracile nucleus by two afferent pathways in the rat," Exp. Neurol.,36, 197 (1972).

  37. 37.

    T. Tömböl, F. Hajau, and I. Marticsek, "A qualitative and quantitative analysis of cuneate and gracile nuclei of the dorsal column fibers," Anat. Anz. Erg.,1, 425 (1971).

  38. 38.

    D. L. Winter, "Gracilis of cat. Functional organization and corticofugal effects," J. Neurophysiol.,28, 48 (1965).

Download references

Additional information

I. P. Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. Translated from Neirofiziologiya, Vol. 6, No. 2, pp. 161–167, March–April, 1974.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Musyashchikova, S.S., Sinyaya, M.S. Activation of the nuclei of Goll and Burdach in the medulla oblongata by visceral afferent systems. Neurophysiology 6, 127–132 (1974). https://doi.org/10.1007/BF01062748

Download citation

Keywords

  • Latent Period
  • Medulla Oblongata
  • Potential Method
  • Recording Electrode
  • Pelvic Nerve