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Half-life of diphenylpyraline in man

  • G. Graham
  • A. G. Bolt
Article

Abstract

The biological half- life of diphenylpyraline was determined in five healthy subjects from the urinary excretion of the unchanged drug. Half-lives ranged from 24 to 40 hr.

Key words

gas Chromatographic assay of diphenylpyraline urinary excretion half-life of diphenylpyraline 

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References

  1. 1.
    M. Rowland. Amphetamine blood and urine levels in man.J. Pharm. Sci. 58: 508–509 (1969).PubMedCrossRefGoogle Scholar
  2. 2.
    E. A. Guggenheim. On the determination of the velocity constant of a unimolecular reaction.Phil. Mag. 2: 538–543 (1926).CrossRefGoogle Scholar
  3. 3.
    A. H. Beckett and M. Rowland. Urinary excretion kinetics of amphetamine in man.J. Pharm. Pharmacol. 17: 628–639 (1965).PubMedCrossRefGoogle Scholar
  4. 4.
    W. W. Douglas. Histamine and antihistamines; 5-hydroxytryptamine and antagonists. In L. S. Goodman and A. Gilman (eds.),The Pharmacological Basis of Therapeutics, Macmillan, New York, 1970, pp. 621–662.Google Scholar

Copyright information

© Plenum Publishing Corporation 1974

Authors and Affiliations

  • G. Graham
    • 1
  • A. G. Bolt
    • 1
  1. 1.Riker Laboratories Australia Pty. Ltd.HornsbyAustralia

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