Journal of Neuro-Oncology

, Volume 25, Issue 2, pp 161–166

Successful treatment for solitary brain metastasis from alveolar soft part sarcoma

  • Cheng -Hsu Wang
  • Ning Lee
  • Liang -Shong Lee
Clinical Study

Abstract

Following pulmonary metastases, alveolar soft part sarcoma has an unexplained predisposition to metastasize to the brain. Herein, a case of alveolar soft part sarcoma solitarily metastatic to the brain is described. A 23-year old female underwent the resection of alveolar soft part sarcoma from the right thigh. Three years after the surgery, a brain tumor was resected and pathology proved it was a metastatic alveolar soft part sarcoma. She is currently alive and well 6 years after brain surgery. Our report suggests that surgical resection for solitary brain metastasis from alveolar soft part sarcoma is an effective treatment modality.

Key words

brain metastasis alveolar soft part sarcoma solitary brain metastasis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Lewis AJ: Sarcoma metastatic to the brain. Cancer 61: 593–601, 1988Google Scholar
  2. 2.
    Liberman PH, Foote Jr FW, Stewart FW, Rerg JW: Alveolar soft part sarcoma. JAMA 198: 1047–1051, 1966Google Scholar
  3. 3.
    Christopherson VM, Foote FM, Stewart FW: Alveolar soft part sarcoma: structurally characteristic tumors of uncertain histogenesis. Cancer 5: 100–111, 1952Google Scholar
  4. 4.
    Enzinger FM, Weiss S: Soft tissue tumor. Mosby, St Louis, pp 780–784, 1982Google Scholar
  5. 5.
    DeSchryver-Kecskemeti K, Kraus FT, Engleman W, Lacy PE: Alveolar soft part sarcoma — a malignant angioreninoma, histochemical, immunohistochemical, and electronmicroscopic study of four cases. Am J Surg pathol 6: 5–18, 1982Google Scholar
  6. 6.
    Fisher ER: Histochemical observations on an alveolar soft part sarcoma with reference to histogenesis. Am J Pathol 32: 721–737, 1956Google Scholar
  7. 7.
    Fisher ER, Reidbord H: Electron microscopic evidence suggestion the myogenous on an alveolar soft part sarcoma with reference to histogenesis. Cancer 27: 150–159, 1971Google Scholar
  8. 8.
    Karnauchow PH, Magner D: The histogenesis of alveolar soft part sarcoma. J Pathol 86: 169–177, 1963Google Scholar
  9. 9.
    Marshall RB, Horn RC Jr: Non-chromaffin paraganglia: comparative study. Cancer 14: 779–787, 1961Google Scholar
  10. 10.
    Mathew T: Evidence supporting neural crest origin of an alveolar soft part sarcoma: an ultrastructural study. Cancer 50: 507–514, 1982Google Scholar
  11. 11.
    Smetana HF, Scott WF: Malignant tumors of non-chromaffin paraganglia. Milit Surg 109: 330–349, 1951Google Scholar
  12. 12.
    Unni KK, Soule EH: Alveolar soft part sarcoma: an electron microscopic study. Mayo Clin Proc 50: 591–598, 1975Google Scholar
  13. 13.
    Welsh RA, Bray DM, Shipkey FH, Meyer AT: Histogenesis of alveolar soft part sarcoma. Cancer 29: 191–204, 1972Google Scholar
  14. 14.
    Mukai M, Torikata C, Hisami I, Atsuo M, Hideya H, Kanefusa K, Keizo K: Histogenesis of soft part sarcoma — An immunohistochemical and biochemical study. Am J Surg Pathol 10: 212–218, 1986Google Scholar
  15. 15.
    Ordonez NG, Hickey RC, Brooks TE: Alveolar soft part sarcoma — A cytologic and immunohistochemical study. Cancer 61: 525–531, 1988Google Scholar
  16. 16.
    Shipkey FH, Liberman PH, Foote FW, Stewart FW: Ultrastructure of alveolar soft part sarcoma. Cancer 17: 821–830, 1964Google Scholar
  17. 17.
    Ekfors TO, Kalimo H, Rantakokko V, Latvala M, Parvinen M: Alveolar soft part sarcoma: a report of two cases with some histochemical and ultrastructural observation. Cancer 43: 1672–1677, 1979Google Scholar
  18. 18.
    Mukai M, Torikata C, Iri H, Kageyama K, Nakalima T, Ueno N, Hirose S, Murakami K: Alveolar soft part sarcoma. A review on it histogenesis and further studies based on electron microscopy, immunohistochemistry and biochemistry. Am J Surg Pathol 7: 679–689, 1983Google Scholar
  19. 19.
    Mukai M, Torikata C, Iri H, Mikata A, Sakamoto T, Hanaoka H, Shinohara C, Baba N, Kanaya K, Kageyama K: Alveolar soft part sarcoma. An elaboration of a three-dimension configuration of the crystalloids by digital image processing. Am J Pathol 116: 398–406, 1984Google Scholar
  20. 20.
    Liberman PH, Brennan MF, Kimmel M, Erlandson RA, Garin-Chesa P, Flehinger BY: Alveolar soft part sarcoma — a clinico pathologic study of half a century. Cancer 63: 1–13, 1989Google Scholar
  21. 21.
    Evans HL: Alveolar soft part sarcoma: a study of 13 typical examples and one with a histologically atypical component. Cancer 55: 912–917, 1985Google Scholar
  22. 22.
    Auerbach HE, Brooks JJ: Alveolar soft part sarcoma. A clinicopathologic and immunohistochemical study. Cancer 60: 66–73, 1987Google Scholar
  23. 23.
    Bryant BM, Wiltshaw E: Central nervous system involvement in sarcoma. Eur J Cancer 16: 1503–1507, 1980Google Scholar
  24. 24.
    Batson OV: Function of vertebral veins and their role in spread of metastasis. Ann Surg 112: 138–149, 1940Google Scholar
  25. 25.
    Wanger JA: Neuropathology of neoplastic metastasis to brain. South MJ 50: 302–305, 1955Google Scholar
  26. 26.
    Chason JL, Walter FB, Landers JW: Metastatic carcinoma in the central nervous system and dorsal root ganglia — a prospective autopsy study. Cancer 16: 781–787, 1963Google Scholar
  27. 27.
    Bindal RK, Sawaya RE, Leavens ME, Taylor SH, Guinee VF: Sarcoma metastatic to the brain: result of surgical treatment. Neurosurgery 35: 185–191, 1994Google Scholar
  28. 28.
    Wronski M, Arbit E, Burt M, Perino G, Galicich JH, Brennan MF: Resection of brain metastases from sarcoma. Ann Surg Oncol 1995; 2: (in press)Google Scholar
  29. 29.
    Espana P, Chang P, Wiernik P: Increased incidence of brain metastases in sarcoma patients. Cancer 45: 377–380, 1980Google Scholar
  30. 30.
    Ho KL: Sarcoma metastatic to the central nervous system: report of three cases and review of the literature. Neurosurgery 5: 44–48, 1979Google Scholar
  31. 31.
    Lilehei KO, Kleinschmidt-DeMasters B, Mitchell DH, Spector E, Kruse CA: Alveolar soft part sarcoma: an unusually long interval between presentation and brain metastasis. Hum Pathol 24: 1030–1034, 1993Google Scholar

Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Cheng -Hsu Wang
    • 1
  • Ning Lee
    • 2
  • Liang -Shong Lee
    • 3
  1. 1.Division of Hematology-Oncology, Department of Internal MedicineChang Gung Memorial HospitalTaiwanTaiwan, Republic of China
  2. 2.Pathology DepartmentChang Gung Memorial HospitalTaiwanTaiwan, Republic of China
  3. 3.Neurosurgery DepartmentVeterans General HospitalTaipeiTaiwan, Republic of China

Personalised recommendations