With local thermal and mechanical stimulation in precise experiments on cats, a study was made of changes in impulse activity of afferent fibers of spinal dorsal roots connected with skin thermoreceptors in the extremities. Psychophysiological studies were done on the characteristics of thermosensitive points of the skin of the upper extremities of man. According to changes in average frequency of impulse activity, dynamic sensitivity, latent period of reaction, and thresholds of temperature and mechanical sensitivity, three groups of heat receptors and two of cold receptors were identified in the skin of the cat. All heat and cold receptors are mechanosensitive. According to quality and intensity of perceptions elicited by thermal stimulation and thresholds of sensitivity to mechanical and temperature effects, thermosensitive points in human skin can also be divided into three groups of heat receptors and two groups of cold receptors. All heat and cold points are mechanosensitive. An analogy between the skin thermoreceptors of animals and man is suggested.
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I. Ya. Kleinbok, ,“Spinal control of afferent temperature information in the cat,” Neirofiziologiya,18, No. 6, 773–779 (1986).
I. Ya. Kleinbok and V. L. Mel'nikov, ,“Change in afferent activity with temperature stimulation of the skin of the fore leg,” Fiziol. Zh. SSSR,69, No. 1, 140–145 (1983).
V. A. Konstantinov, N. K. Danilova, and K. P. Ivanov, ,“Effect of temperature of various skin layers on impulsation of cold thermoreceptors,” Ibid.,66, No. 6, 902–907 (1980).
V. A. Konstantinov, N. K. Danilova, and K. P. Ivanov, ,“Changes in impulsation of cold thermoreceptors of the skin depending on temperature of its various layers,” Ibid., No. 12, 1785–1791.
V. A. Konstantinov, N. K. Danilova, and K. P. Ivanov, ,“Localization of cold thermoreceptors in various skin layers,” Ibid.,69, No. 2, 204–209 (1983).
S. Zh. Tleulin, V. N. Doronin, and I. Ya. Kleinbok, ,“Reaction of spontaneously active neurons of the spinal cord to temperature stimulation of the skin,” Neirofizioloviya,6, No. 2, 168–174 (1974).
E. Dodt and Y. Zotterman, ,“Mode of action of warm receptors,” Acta Physiol. Scand.,26, No. 2, 345–357 (1952).
R. Declaux, ,“Lies recepteurs thermiques cutanes,” J. Physiol.,73, No. 6, 846–862 (1977).
R. Duclaux and D. R. Kenshalo, ,“Response characteristics of cutaneous warm receptors in the monkey,” J. Neurophysiol.,43, No. 1, 1–15 (1980).
R. W. Dykes, ,“Coding of steady and transient temperature by cutaneous ‘cold’ fibers serving the hand of monkeys,” Brain Res.,98, No. 3, 485–500 (1975).
R. F. Hellon, H. Hensel, and K. Schafer, ,“Thermal receptors in the scrotum of the rat,” J. Physiol.,248, No. 2, 349–357 (1975).
H. Hensel, ,“Spezifische Warmeimpulse aus Nacenregion der Katze,” Pflugers Arch.,302, No. 4, 374–376 (1968).
H. Hensel, ,“Temperature receptors in the skin,” Soc. Ref.,41, No. 3, 442–462 (1970).
H. Hensel and K. K. A. Boman, ,“Afferent impulses in cutaneous sensory nerves in human subjects,” J. Neurophysiol.,238, No. 5, 564–578 (1960).
H. Hensel and T. Huopaniemi, ,“Static and dynamic properties of warm fibers in the intra-orbital nerve,” Arch. Ges. Physiol.,309, No. 1, 1–10 (1969).
H. Hensel and A. Iggo, ,“Analysis of cutaneous warm and cold fibers in primates,” Pflugers Arch.,329, No. 1, 1–8 (1971).
A. Iggo, ,“Cutaneous heat and cold receptors with slowly-conducting (C) afferent fibers,” Quart. J. Exp. Physiol.,44, No. 3, 362–370 (1959).
A. Iggo, ,“Cutaneous thermoreceptors in primates and subprimates,” J. Physiol., No. 2, 403–430 (1969).
A. Iggo, ,“Cutaneous thermoreceptors,” in: Somatosensory Mechanisms: Proc. Intern. Sympos., Stockholm (1983), pp. 216–272 (1983).
A. Iggo and R. Ramsey, ,“Thermosensory mechanisms in the spinal cord of monkey,” in: Sensory Function, Skin Primat. Spec. Ref. Man. Proc. Intern. Sympos, Stockholm (1976), pp. 285–302.
K. O. Johnson, I. Darian-Smith, and C. Lamotte, ,“Peripheral neural determinants of temperature discrimination in man. A correlative study of responses to cooling skin,” J. Neurophysiol.,36, No. 2, 347–370 (1973).
D. R. Kenshalo, ,“Correlations of temperature sensitivity in man and monkey: a first approximation,” in: Sensory Functions of the Skin in Primates, Y. Zotterman (ed.), Pergamon, New York (1976), pp. 305–330.
R. H. Lamotte and J. G. Thalhammer, ,“Response properties of high-threshold cutaneous cold receptors in the primate,” Brain Res.,244, No. 2, 279–287 (1982).
F. K. Pierau, P. Torrey, and D. O. Carpenter, ,“Mammalian cold receptor afferents: role of an electrogenic sodium pump in sensory transduction,” Ibid.,73, No. 1, 156–160 (1974).
D. D. Price and A. C. Browe, ,“Spinal cord coding of graded non-noxious and noxious temperature increases,” J. Neurol.,48, 201–221 (1975).
D. A. Poulos and R. A. Lende, ,“Response of trigeminal ganglion neurons to thermal stimulation of oral-facial regions. II. Temperature change response,” J. Neurophysiol.,33, No. 5, 518–526 (1970).
R. Siminoff, ,“Cutaneous nerve activity in response to temperature changes of the cat's skin,” Exp. Neurol.,11, No. 1, 171–181 (1965).
G. Weddell and S. Miller, ,“Cutaneous sensibility,” Annu. Rev. Physiol.,24, No. 1, 199–222 (1962).
Institute of Physiology, Kazakhstan, Academy of Sciences. Translated from Neirofiziologiya, Vol. 24, No. 3, pp. 314–322, May–June, 1992.
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Kleinbok, I., Gabdullina, E. Characteristics of thermo-mechanosensitive receptors in human and animal skin. Neurophysiology 24, 203–208 (1992). https://doi.org/10.1007/BF01057168
- Latent Period
- Temperature Effect
- Human Skin
- Dorsal Root
- Mechanical Stimulation