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2,3,7,8-Tetrachlorodibenzo-p-dioxin toxic effects and tissue levels in animals from the contaminated area of seveso, Italy


After the environmental contamination by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the area of Seveso, Italy, thousands of small domestic animals (mainly rabbits and poultry) died within a few weeks. Autopsies on dead animals showed various pathological signs, such as hepatic lesions and haemorrhage. TCDD was monitored in animal tissues by gas chromatography-mass fragmentography; rabbit liver levels corresponded fairly well to soil contamination, which indicated that this species can be used as a tool for tracking the presence of TCDD in the environment.

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Correspondence to R. Fanelli or S. Garattini.

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Fanelli, R., Bertoni, M.P., Castelli, M.G. et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin toxic effects and tissue levels in animals from the contaminated area of seveso, Italy. Arch. Environ. Contam. Toxicol. 9, 569–577 (1980).

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  • Waste Water
  • Water Management
  • Water Pollution
  • Toxic Effect
  • Domestic Animal