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Cadmium and zinc interactions in fish: Effects of zinc on the uptake, organ distribution, and elimination of109Cd in the zebrafish,Brachydanio rerio

  • Anders Wicklund
  • Per Runn
  • Leif Norrgren
Article

Abstract

The fate of equal nondietarian “pulses” of109Cd was studied in the zebrafish,Brachydanio rerio, at two Cd water concentrations (<0,05 Μg/L and 1 Μg/L) during Zn (10 Μg/L) exposure periods of various duration. This approach was used to investigate Cd-Zn interactions at subacute toxicity levels. There was no effect of Zn on the109Cd uptake by the whole body and gills. An antagonistic effect of Zn, on the109Cd uptake, was revealed in the intestine. Zn tended to increase the109Cd elimination rate in the gills at the higher Cd level, while retarding the elimination from the gastro-intestinal tract. Zn also increased the amount of109Cd retained in the liver and, under certain conditions, in the kidney. A simple mathematical description of109Cd elimination and accumulation for the various organs is presented. Proposed mechanisms for metal-metal interactions are discussed in an attempt to explain the present results.

Keywords

Zinc Cadmium Water Concentration Elimination Rate Exposure Period 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc 1988

Authors and Affiliations

  • Anders Wicklund
    • 1
  • Per Runn
    • 1
  • Leif Norrgren
    • 2
  1. 1.Department of ZoologyUppsala UniversityUppsalaSweden
  2. 2.Department of Pathology, Faculty of Veterinary MedicineSwedish University of Agricultural SciencesUppsalaSweden

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