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Preganglionic parasympathetic innervation in normal and partially denervated rat stomach

Abstract

Retrograde transport of horseradish peroxidase (HRP) was used to study the organization of the preganglionic parasympathetic innervation of the normal and vagotomized rat stomach. In normal rats, following application of HRP to either the gastric fundus or corpus, HRP accumulated bilaterally in nerve cells in the dorsal vagal motor nuclei, but predominantly in the left nucleus. The biggest populations of cells innervated the lesser curvature of the stomach. When HRP was applied at different periods of time after truncal or selective proximal vagotomy, there was no labeling of nerve cells in the dorsal vagal motor nuclei. Regeneration of efferent vagal nerve fibers and the recovery of gastric activity is discussed.

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Additional information

A. A. Bogomolets Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev. Institute of Physiology, T. G. Shevchenko Kiev State University. Translated from Neirofiziologiya, Vol. 23, No. 2, pp. 231–238, March–April, 1991.

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Voitenko, L.P., Polinkevich, B.S., Beregovaya, T.V. et al. Preganglionic parasympathetic innervation in normal and partially denervated rat stomach. Neurophysiology 23, 181–186 (1991). https://doi.org/10.1007/BF01054142

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Keywords

  • Nerve Fiber
  • Horseradish Peroxidase
  • Nerve Cell
  • Vagal Nerve
  • Retrograde Transport