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Glycoconjugate Journal

, Volume 5, Issue 1, pp 3–8 | Cite as

Glycosidations with thioglycosides activated by sulfuryl chloride/trifluoromethanesulfonic acid: synthesis of a human blood group B trisaccharide glycoside

  • Elisabeth Kallin
  • Hans Lönn
  • Thomas Norberg
Article

Abstract

The trisaccharide 2-(p-trifluoroacetamidophenyl)ethyl 2-O-(α-l-fucopyranosyl)-3-O-(α-d-galactopyranosyl)-β-d-galactopyranoside, corresponding to the human blood group B determinant, was synthesized. Thioglycosides activated by sulfuryl chloride/trifluoromethanesulfonic acid were used as glycosyl donors in the construction of the three glycosidic linkages.

Key words

synthesis thioglycosides blood group B trisaccharide 

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Copyright information

© Glycoconjugate Journal 1988

Authors and Affiliations

  • Elisabeth Kallin
    • 1
  • Hans Lönn
    • 2
  • Thomas Norberg
    • 2
  1. 1.Department of Carbohydrate ChemistryUniversity of LundLundSweden
  2. 2.Organic Synthesis DepartmentBioCarb ABLundSweden

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