Biotechnology Letters

, Volume 8, Issue 4, pp 253–256

Continuous acetone-butanol fermentation with high productivity by cell ultrafiltration and recycling

  • P. Pierrot
  • M. Fick
  • J. M. Engasser
Article

Abstract

To increase the productivity of the acetone-butanol fermentation, a hollow-fiber ultrafilter is used to separate and recycle cells in a continuous fermentation ofClostridium acetobutylicum. Under partial cell recycling and at a dilution rate of 0.5 hr−1, a cellular concentration of 20 g/l and a solvent productivity of 6.5 g/l.hr is maintained for several days at a total solvent concentration of 13 g/l.

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References

  1. Bahl H., Andersch W., Gottschalk G. (1982) Eur. J. Appl. Microbiol. Biotechnol.15, 201–205.Google Scholar
  2. Fick M., Pierrot P. and Engasser J.M. (1985) Biotechnol. Letters7, 503–508Google Scholar
  3. Fick M., (1986) Thesis INPL, NancyGoogle Scholar
  4. Monot F. and Engasser J.M. (1983) Eur. J. Appl. Microbiol. Biotechnol.18, 246–248.Google Scholar

Copyright information

© Science and Technology Letters 1986

Authors and Affiliations

  • P. Pierrot
    • 1
  • M. Fick
    • 1
  • J. M. Engasser
    • 1
  1. 1.Laboratoire des Sciences du Génie ChimiqueCNRS-ENSIC Institut National Polytechnique de LorraineNancy cedexFrance

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