Biotechnology Letters

, Volume 13, Issue 2, pp 97–100 | Cite as

Influence of growth rate on the accumulation of ergosterol in yeast-cells in a phosphate limited continuous culture

  • C. Arnezeder
  • W. A. Hampel
Article

Summary

The influence of the growth rate on the accumulation of ergosterol inSaccharomyces cerevisiae was studied with glucose and ethanol as substrates under P-limitation in chemostat experiments. In cultures with glucose as carbon source a decrease in ergosterol content with dilution rates up to 0.08 h−1 was observed, whereas above this dilution rate an increase in ergosterol content occurred. Similar but less marked effects were attained with ethanol as carbon source. A maximum specific rate of ergosterol synthesis of about 2.4 mg per h and g dry cell mass was calculated for phosphorus limited cultures.

Keywords

Glucose Phosphorus Carbon Source Bioorganic Chemistry Cell Mass 
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Copyright information

© Kluwer Academic Publishers 1991

Authors and Affiliations

  • C. Arnezeder
    • 1
  • W. A. Hampel
    • 1
  1. 1.Institute of Biochemical Technology and MicrobiologyTechnical University of ViennaVienna(Austria)

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