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Biotechnology Letters

, Volume 7, Issue 2, pp 81–86 | Cite as

Novel use of a perfluorocarbon for supplying oxygen to aerobic submerged cultures

  • Dominick Damiano
  • Shaw S. Wang
Article

Summary

A novel method for supplying oxygen by using a perfluorocarbon as an oxygen carrier in submerged cultures was demonstrated. Oxygen was transferred to the aqueous phase by liquid-liquid contacting in a spray column fermentor. Advantages of using such a system for supplying oxygen are discussed.

Keywords

Oxygen Organic Chemistry Aqueous Phase Bioorganic Chemistry Submerged Culture 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Nomenclature

F1

recirculation rate of PP9 through nozzle

PB

back pressure at nozzle

SAPP9

oxygen concentration in PP9 in aerator as a percent of saturation when air equilibrated at the end of the exponential phase of growth

TF

fermentation time to reach final cell concentration

VA

air flow rate through sparger

Xe

cell concentration at the end of the exponential phase of growth

XF

final cell concentration

ØA

gas (air) hold-up

ØL

liquid (PP9) hold-up in aqueous system

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References

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Copyright information

© Science and Technology Letters 1985

Authors and Affiliations

  • Dominick Damiano
    • 1
  • Shaw S. Wang
    • 1
  1. 1.Department of Chemical and Biochemical Engineering RutgersThe State University of New JerseyPiscatawayUSA

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