Biotechnology Letters

, Volume 10, Issue 10, pp 689–694

Influence of bovine serum albumin on the growth of hybridoma cells in airlift loop reactors using serum-free medium

  • Manfred Hülscher
  • Ulfert Onken


Hybridoma cells were grown in serum-free media using different culture systems: stationary culture, spinner flask and a laboratory-scale airlift loop reactor. Influence of bovine serum albumin (BSA) on growth and product formation was only found in the airlift loop reactor.


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Copyright information

© Kluwer Academic Publishers 1988

Authors and Affiliations

  • Manfred Hülscher
    • 1
  • Ulfert Onken
    • 1
  1. 1.Fachbereich Chemietechnik, Lehrstuhl für Technische Chemie BUniversität DortmundDortmund 50F R Germany

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