Ultrastructural localization of calcitonin, somatostatin and serotonin in parafollicular cells of rat thyroid
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- Zabel, M. Histochem J (1984) 16: 1265. doi:10.1007/BF01003725
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Three hormones were demonstrated in ultrathin sections of the rat thyroid using immunocytochemical methods with either a PAP complex or a protein A-gold complex as the tabel. In control rats, calcitonin was found to be present in all parafollicular cells and somatostatin in occasional cells. In rats pretreated with 5-hydroxytryptophan, serotonin was detected in all parafollicular cells as well. In serial ultrathin sections, the three hormones were seen to be localized in the same secretory granules.