Xanthogranulomatous pyelonephritis in childhood Report of three cases and a review of the literature
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Abstract
Xanthogranulomatous pyelonephritis (XPN) is a rare, unilateral manifestation of chronic pyelonephritis. It is characterized by extensive damage to the parenchyma and its replacement by xanthogranulomatous tissue. The main roentgenological feature is a functionless kidney, often with calcfication. The clinical, pathological and roentgenological findings of our three patients are analyzed and compared with previously reported findings, most notably those in childhood. A tentative diagnosis of XPN can be made from intravenous urography and echography of the kidney. In general, angiography does not provide additional pathognomonic features. The final diagnosis of XPN can only be made by histological microscopic examination. The prognosis of this disease is considered to be good, when the affected kidney is removed and function on the contralateral side is good.
Key words
Xanthogranulomatous pyelonephritis Tumor Nonfunctioning kidney Foam cells Angiography UltrasonographyPreview
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