Pediatric Radiology

, Volume 11, Issue 1, pp 42–45 | Cite as

Infantile hepatic hemangioendothelioma with subsequent malignant degeneration

  • S. G. Kirchner
  • R. M. Heller
  • A. G. Kasselberg
  • H. L. Greene
Short Reports

Abstract

A 4 year old child was seen because of an enlarging epigastric mass and a rapidly falling hematocrit 31/2 years following steroid treatment for multiple hepatic hemangioendotheliomas. Technetium 99 m sulfur colloid liver scan and hepatic angiography confirmed the presence of a large, vascular mass involving the left lobe of the liver. A left hepatic lobectomy was performed and histopathology showed angiosarcoma. As children with hemangioendotheliomas of the liver begin to survive for longer periods of time, surveillance for the possible development of neoplastic disease is recommended.

Key words

Hemangioendothelioma, hepatic Hemangioendothelioma, malignant degeneration Angiosarcoma, hepatic Neoplasm, hepatic 

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References

  1. 1.
    Al-Rashid RA (1971) Cyclophosphamide and radiation therapy in the treatment of hemangioendothelicma with disseminated intravascular clotting. Cancer 27: 364PubMedGoogle Scholar
  2. 2.
    Dehner LP, Ishak KG (1971) Vascular tumors of the liver in infants and children. Arch Pathol Lab Med 92: 101Google Scholar
  3. 3.
    deLorimier AA, Simpson EB, Baum RS, Carlsson E (1967) Hepatic artery ligation for hepatic hemangiomatosis. N Engl J Med 277: 333PubMedGoogle Scholar
  4. 4.
    Jackson C, Greene HL, O'Neill J, Kirchner S (1977) Hepatic hemangioendothelioma. Angiographic appearance and apparent prednisone responsiveness. Am J Dis Child 131: 74PubMedGoogle Scholar
  5. 5.
    McSweeney WJ, Potter BM, Majd M (1980) Diffuse infantile hepatic hemangiomata (hemangioendothelioma): Changing concepts in diagnosis. Presented at the 23rd annual meeting of the Society for Pediatric Radiology, Salt Lake City, Utah, April 18–20Google Scholar
  6. 6.
    Miller JH, Gates GF, Stanley P (1977) The radiologic investigation of hepatic tumors in childhood. Radiology 124: 451PubMedGoogle Scholar
  7. 7.
    Moss AA, Clark RE, Palubinskas AJ, deLorimier AA (1971) Angiographic appearance of benign and malignant hepatic tumors in infants and children. AJR 113: 61Google Scholar
  8. 8.
    Rotan M, John M, Stowe S, Inamdar S (1980) Radiation treatment of pediatric hepatic hemangiomatosis and coexisting cardiac failure. N Engl J Med 302: 852PubMedGoogle Scholar
  9. 9.
    Stanley P, Gates GF, Eto RT, Miller SW (1977) Hepatic cavernous hemangiomas and hemangioendotheliomas in infancy. AJR 129: 317PubMedGoogle Scholar
  10. 10.
    Tewfik H, Latourette H, Christie J, Twefik F (1977) Infantile hepatic hemangioendothelioma. A surviving case. Radiology 123: 723PubMedGoogle Scholar
  11. 11.
    Touloukian RJ (1970) Hepatic hemangioendothelioma during infancy: Pathology, diagnosis and treatment with prednisone Pediatrics 15: 71Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • S. G. Kirchner
    • 1
  • R. M. Heller
    • 1
  • A. G. Kasselberg
    • 2
  • H. L. Greene
    • 3
  1. 1.Department of Radiology and Radiological SciencesVanderbilt University Medical CenterNashvilleUSA
  2. 2.Department of PathologyVanderbilt University Medical CenterNashvilleUSA
  3. 3.Department of PediatricsVanderbilt University Medical CenterNashvilleUSA

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