Neurochemical Research

, Volume 3, Issue 6, pp 755–762 | Cite as

PhenylethanolamineN-methyltransferase from the brain and adrenal medulla of the rat

A comparison of their properties
  • Peter H. Yu
Original Articles
Accepted:

Abstract

Two different molecular forms of phenylethanolamineN-methyltransferase (PNMT, EC 2.1.1) have been isolated from the brain and adrenal glands of the rat as indicated by certain of their physicochemical properties, such as: molecular weight estimated on the basis of gel chromatography of Sephadex G-100; pH optima; electrophoretic mobility on acrylamide gel; and steady-state kinetic parameters. The highKm value for the brain PNMT has been assumed to be responsible for the low methylation ratio between norepinephrine and epinephrine in the CNS.

Keywords

Molecular Weight Norepinephrine Epinephrine Kinetic Parameter Physicochemical Property 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Peter H. Yu
    • 1
  1. 1.Psychiatric Research DivisionUniversity HospitalSaskatoonCanada

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