Journal of Computational Neuroscience

, Volume 1, Issue 4, pp 313–321 | Cite as

When inhibition not excitation synchronizes neural firing

  • Carl Van Vreeswijk
  • L. F. Abbott
  • G. Bard Ermentrout
Article

Abstract

Excitatory and inhibitory synaptic coupling can have counter-intuitive effects on the synchronization of neuronal firing. While it might appear that excitatory coupling would lead to synchronization, we show that frequently inhibition rather than excitation synchronizes firing. We study two identical neurons described by integrate-and-fire models, general phase-coupled models or the Hodgkin-Huxley model with mutual, non-instantaneous excitatory or inhibitory synapses between them. We find that if the rise time of the synapse is longer than the duration of an action potential, inhibition not excitation leads to synchronized firing.

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Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Carl Van Vreeswijk
    • 1
  • L. F. Abbott
    • 1
  • G. Bard Ermentrout
    • 2
  1. 1.Center for Complex SystemsBrandeis UniversityWaltham
  2. 2.Department of MathematicsUniversity of PittsburghPittsburgh

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