New method for preparation of 2-bromothiophene

  • Ya. L. Gol'dfarb
  • A. A. Dudinov
  • V. P. Litvinov
Brief Communications


The reaction of KBrO3 with thiophene in the presence of HBr in a two-phase water-ether system permits obtaining 2-bromothiophene, not contaminated with 2,5-dibromothiophene, in high yield.


Thiophene KBrO3 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Literature cited

  1. 1.
    N. R. Clark, Manufactur. Chem. and Aerosol News,43, 23 (1972).Google Scholar
  2. 2.
    A. P. Terent'ev, L. I. Belen'kii, and L. A. Yanovskaya, Zh. Obshch. Khim.,24, 1265 (1954).Google Scholar
  3. 3.
    A. McKillop, D. Bromley, and E. C. Taylor, J. Org. Chem.,37, 88 (1972).Google Scholar
  4. 4.
    Ya. L. Gol'dfarb and M. L. Kirmalova, Zh. Obshch. Khim.,26, 3409 (1956).Google Scholar
  5. 5.
    M. L. Kirmalova, Dissertation, Moscow (1958).Google Scholar
  6. 6.
    A. R. Butler and J. B. Hendry, J. Chem. Soc. B,1970, 170.Google Scholar
  7. 7.
    N. C. Deno and N. H. Potter, J. Am. Chem. Soc.,89, 3550 (1967).Google Scholar
  8. 8.
    H. D. Hartough, Thiophene and Its Derivatives, Wiley-Interscience, New York (1952), p. 208.Google Scholar

Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Ya. L. Gol'dfarb
    • 1
  • A. A. Dudinov
    • 1
  • V. P. Litvinov
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRMoscow

Personalised recommendations