Chemistry of Heterocyclic Compounds

, Volume 3, Issue 1, pp 78–79 | Cite as

Researches on atropine-like compounds

I. Synthesis and properties of aminoesters of disbustituted glycolic acids
  • N. N. Yarovenko
  • I. L. Mikhaleva
  • G. Yu. Khlyupina
Article
  • 31 Downloads

Abstract

Transesterification of ethyl esters of phenyl-2-thiazolyl and phenyl-p-chlorophenylglycolic acid by N-methyl-4-hydroxypiperidine gives N-methyl-4-piperidyl esters of phenyl-2-thiazolyl- and phenyl-p-chlorophenylglycolic acid. Transesterification of the alkyl esters gives aminoesters of disubstituted glycolic acids in lower yield than reaction of the corresponding acids with halogenoalkylamines.

Keywords

Ester Ethyl Organic Chemistry Lower Yield Transesterification 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    S. G. Kuznetsov and S. N. Golikov, Synthetic Atropine-like Compounds [in Russian], Leningrad, 1962.Google Scholar
  2. 2.
    J. H. Biel, E. P. Sprengeler, H. A. Leiser, J. Horner, A. Drukker, and H. L. Friedman, J. Am. Chem. Soc.,77, 2250, 1955.Google Scholar
  3. 3.
    S. B. Coan, B. Jaffe, and D. T. Papa, J. Chem. Soc.,78, 3701, 1956.Google Scholar
  4. 4.
    R. R. Burtner and J. W. Cusis, J. Am. Chem. Soc.,65, 262, 1943.Google Scholar
  5. 5.
    S. R. Torf, N. V. Khromov-Borisov, and M. L. Gindenbom, Med. prom.,65, 262, 1943.Google Scholar
  6. 6.
    J. Klosa, J. pr. Chem.,21, 1, 1962.Google Scholar

Copyright information

© The Faraday Press, Inc. 1969

Authors and Affiliations

  • N. N. Yarovenko
  • I. L. Mikhaleva
  • G. Yu. Khlyupina

There are no affiliations available

Personalised recommendations