Chemistry of Heterocyclic Compounds

, Volume 3, Issue 1, pp 34–35 | Cite as

Synthesis of 1,3-oxazine derivatives based on diketene

  • V. I. Gunar
  • I. A. Mikhailopulo
  • L. F. Ovechkina
  • S. I. Zav'yalov
Article
  • 37 Downloads

Abstract

Reaction of diketene with potassium cyanate in acetic acid gives 6-methyl-2,3-dihydro-2,4-diketo-1,3-oxazine, also formed by cyclizing acetoacetylurethane, or by treating ammonium thiocyanate with diketene in the presence of mercuric acetate. Acetylation of N-trisubstituted ureas with ketene in acetic acid gives N-alkyl derivatives of 6-methyl-2,3-dihydro-2,4-diketo-1,3-oxazine.

Keywords

Acetic Ammonium Potassium Urea Acetic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© The Faraday Press, Inc. 1969

Authors and Affiliations

  • V. I. Gunar
    • 1
  • I. A. Mikhailopulo
    • 1
  • L. F. Ovechkina
    • 1
  • S. I. Zav'yalov
    • 1
  1. 1.Zelinskii Institute of Organic ChemistryAS USSRMoscow

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