Origins of life

, Volume 14, Issue 1–4, pp 485–488 | Cite as

Self-sequencing of amino acids and origins of polyfunctional protocells

  • Sidney W. Fox


The primal role of the origins of proteins in molecular evolution is discussed. On the basis of this premise, the significance of the experimentally established self-sequencing of amino acids under simulated geological conditions is explained as due to the fact that the products are highly nonrandom and accordingly contain many kinds of information. When such thermal proteins are aggregated into laboratory protocells, an action that occurs readily, the resultant protocells also contain many kinds of information. Residue-by-residue order, enzymic activities, and lipid quality accordingly occur within each preparation of proteinoid (thermal protein).

In this paper are reviewed briefly the phenomenon of self-sequencing of amino acids, its relationship to evolutionary processes, other significance of such self-ordering, and the experimental evidence for original polyfunctional protocells.


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Copyright information

© D. Reidel Publishing Company 1984

Authors and Affiliations

  • Sidney W. Fox
    • 1
  1. 1.NFCR Laboratory at the Institute for Molecular and Cellular EvolutionUniversity of MiamiCoral Gables

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