Synthesis of 18,19-bisnor-δ1,3,5(10),13(17)-pregnapentaen-3-ol-20-one methyl ethek
Organic and Biological Chemistry
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Conclusions
A method was developed for the synthesis of S-methoxy-δ1,3,5(10),13(17)-D-homoestrapentaen-Ha-one, from which it was possible to obtain 3-methoxy-18,19-bisnor-δ1,3,5(10),13(17)-pregnapentaen-20-one, a key compound in the total synthesis of 18-cyanosteroids.
Keywords
Methyl Total Synthesis
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