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Cyclosporin A and C

New metabolites fromTrichoderma polysporum (Link ex Pers.) Rifai
  • M. Dreyfuss
  • E. Härri
  • H. Hofmann
  • H. Kobel
  • W. Pache
  • H. Tscherter
Industrial Microbiology

Summary

Cyclosporin A and C are new antifungal antibiotics fromTrichoderma polysporum (Link ex Pers.) Rifai. The metabolites are produced in submerged culture and are extracted therefrom by organic solvents. Cyclosporin A is a nonpolar cyclic peptide with a molecular weight of 1202.6. The cyclosporins exhibit a narrow spectrum of antifungal activity and in addition have immunosuppressive properties.

Keywords

Peptide Molecular Weight Cyclosporin Organic Solvent Antifungal Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • M. Dreyfuss
    • 1
  • E. Härri
    • 1
  • H. Hofmann
    • 1
  • H. Kobel
    • 1
  • W. Pache
    • 1
  • H. Tscherter
    • 1
  1. 1.Pharmaceutical Division, Chemical ResearchSandoz Ltd.BasleSwitzerland

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