Three groups of sheep, one control (A) and two infected withFasciola hepatica metacercariae (B&C), were investigated. Each animal of group B was orally dosed with about 270 metacercariae and each sheep in group C received two such doses administered 14 days apart. In both infected groups, plasma ascorbic acid levels progressively decreased after exposure reaching a minimum by week 9, and then slightly increased during the subsequent five weeks. The decrease in ascorbic acid concentrations was mainly related to impaired synthesis as a result of the hepatic damage caused by the flukes.
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Gameel, A.A. Plasma ascorbic acid levels in sheep experimentally infected withFasciola hepatica . Z. Parasitenkd. 66, 321–326 (1982). https://doi.org/10.1007/BF00925348
- Bile Duct
- Ascorbic Acid Concentration
- Plasma Ascorbic Acid
- Plasma Ascorbate