The carbonylation of ethylene with CO in either an aliphatic or a cyclic secondary amine as the medium, in the presence of mercury acetate, at 150–250° and an initial pressure of 60–75 atm, leads to the formation of the corresponding propionic acid N-substituted amide in up to 50% yield and higher when based on amine taken for reaction.
Under analogous conditions, propionic acid anilide is formed from aniline, C2H4 and CO in up to 80% yield and higher when based on starting amine.
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B. K. Nefedov, N. S. Sergeeva, and Ya. T. Éidus, Izv. Akad. Nauk SSSR, Ser. Khim., 807 (1973).
B. K. Nefedov, N. S. Sergeeva, and Ya. T. Éidus, Izv. Akad. Nauk SSSR, Ser. Khim., 1751, 1753 (1972).
W. Reppe and A. Magin, British Patent No. 672379 (1952); Chem. Abstr.,47, 5428 (1953); W. Reppe, British Patent No. 705791 (1954); Chem. Abstr.,49, 4708 (1955).
H. J. Nienburg and E. Keunecke, German Patent No. 863799 (1953); Chem. Abstr.,48, 1427 (1954).
P. Pino, Italian Patent No. 471913 (1952); Chem. Abstr.,48, 7627 (1954).
N. Kutepow and H. Bille, German Patent No. 921988 (1955); Chem. Abstr.,53, 1150 (1959).
W. Reppe and W. Schweckendik, German Patent No. 805641 (1951); Chem. Abstr.,47, 602 (1953).
A. T. Larson, US Patent No. 2497310 (1950); Chem. Abstr.,44, 4489 (1951).
R. Kh. Freidlina and N. S. Kochetkova, Izv. Akad. Nauk SSSR, Otd. Khim. Nauk, 128 (1945).
Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 608–612, March, 1974.
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Nefedov, B.K., Sergeeva, N.S. & Éidus, Y.T. Carbonylation reaction. Russ Chem Bull 23, 573–576 (1974). https://doi.org/10.1007/BF00921147