Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Properties of lymphocyte chemotactic factor (lymphotactin) in thymus

  • 14 Accesses

  • 2 Citations

Abstract

Aqueous extracts of calf thymus from immunologically stimulated animals contain trypsin- and neuraminidase-labile macromolecules with molecular weights of less than 30,000 daltons which will specifically attract chemotactically lymphocytes. This activity we ascribe to “lymphotactin.”

This is a preview of subscription content, log in to check access.

We’re sorry, something doesn't seem to be working properly.

Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

References

  1. 1.

    McCluskey, R.T., B. Benacerraf, andJ.W. McCluskey. 1963. Studies on the specificity of the cellular infiltrate in delayed hypersensitivity reactions.J. Immunol. 90:466.

  2. 2.

    Ward, P.A., C.R. Offen, andJ.R. Montgomery. 1971. Chemoattractants of leukocytes, with special reference to lymphocytes.Fed. Proc. 30:1721.

  3. 3.

    Houck, J.C., C.M. Chang, andM. Platt. 1973. Macrophage migration inhibitory factor in thymus.Proc. Soc. Exp. Biol. Med. 143:858.

  4. 4.

    Boyum, A. 1968. Ficol-hypaque method for separating mononuclear cells and granulocytes from human blood.Scand. J. Clin. Lab. Invest. Suppl. 77.

  5. 5.

    Ward, P.A. 1974. Leukotaxis and leukotactic disorders.Am. J. Pathol. 77:520.

  6. 6.

    Zipilivan, E. B. Hudson, andW. Blatt. 1969. Separation of immunologically active fragments by membrane partition chromatography.Anal. Biochem. 30:91.

Download references

Author information

Additional information

Supported in part by a contract from the Office of Naval Research N00014-71-C-0203.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Houck, J.C., Chang, C.M. Properties of lymphocyte chemotactic factor (lymphotactin) in thymus. Inflammation 1, 217–221 (1976). https://doi.org/10.1007/BF00917531

Download citation

Keywords

  • Public Health
  • Molecular Weight
  • Internal Medicine
  • Trypsin
  • Macromolecule