Journal of Neurology

, Volume 241, Issue 7, pp 456–459 | Cite as

Delayed cerebellar ataxia complicating falciparum malaria: A clinical study of 74 patients

  • Nimal Senanayake
  • H. J. de Silva
Original Communication


We report the clinical features of 74 patients with delayed cerebellar ataxia (DCA) following falciparum malaria, who were prospectively followed up at two centres. This unusual complication has an acute onset, with signs suggesting a predominantly midline cerebellar lesion without any evidence of cerebral involvement. There was a delay of a median 13 days between the onset of fever and the onset of ataxia. DCA has a good prognosis, with spontaneous and complete recovery within 3 months. In our opinion, it is an example of a post-infective neurological syndrome possibly mediated via an immune mechanism.

Key words

Cerebellar ataxia Falciparum malaria 


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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • Nimal Senanayake
    • 1
  • H. J. de Silva
    • 2
  1. 1.Department of Medicine, Faculty of MedicineUniversity of PeradeniyaPeradeniyaSri Lanka
  2. 2.Department of Medicine, Faculty of MedicineUniversity of KelaniyaKelaniyaSri Lanka

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