Journal of Neurology

, Volume 243, Issue 9, pp 666–667 | Cite as

Increased adhesion of CD4+ and CD14+ mononuclear cells to cultured multiple sclerosis brain endothelial cells

  • Anna Dufour
  • Elena Corsini
  • Sergio Giombini
  • Angelo Nespolo
  • Clara Milanese
  • Andrea Salmaggi
Letter to the Editors

References

  1. 1.
    Beekhuizen H, Blokland I, Corsel-van-Tilburg AJ, Koning F, Furth R van (1991) CD14 contributes to the adherence of human monocytes to cytokinestimulated endothelial cells. J Immunol 147:3761–3767Google Scholar
  2. 2.
    Cannella B, Raine CS (1995) The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 37:424–435Google Scholar
  3. 3.
    Cross AH (1992) Immune cell traffic control and the central nervous system. Semin Neurosci 4:213–219Google Scholar
  4. 4.
    Hafler DA, Weiner HL (1987) In vivo labeling of peripheral blood T-cells using monoclonal antibodies: rapid trafficking into CSF in progressive multiple sclerosis. Ann Neurol 22:90–93Google Scholar
  5. 5.
    Huynh HK, Dorovini-Zis K (1993) Effects of interferon-gamma on primary cultures of human brain microvessel endothelial cells. Am J Pathol 142: 1265–1278Google Scholar
  6. 6.
    Mrsulia BB, Mrsulia BT, Fujimoto T, Klatzo I, Spatz M (1976) Isolation of brain capillaries: a simplified technique. Brain Res 110:361–365Google Scholar
  7. 7.
    Raine CS, Cannella B (1992) Adhesion molecules and central nervous system inflammation. Semin Neurosci 4:201–211Google Scholar
  8. 8.
    Sobel RA, Mitchell ME, Fondren G (1990) Intercellular adhesion molecule I (ICAM-1) in cellular immune reaction in the human central nervous system. Am J Pathol 136:1309–1316Google Scholar
  9. 9.
    Tsukada N, Matsuda M, Miyagi K, Yanagisawa N (1993) Adhesion of cerebral endothelial cells to lymphocytes from patients with multiple sclerosis. Autoimmunity 14:329–333Google Scholar
  10. 10.
    Washington R, Burton J, Todd RF III, Newman W, Dragovic L, Dore-Duffy P (1994) Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis. Ann Neurol 35:89–97Google Scholar

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Anna Dufour
    • 1
  • Elena Corsini
    • 1
  • Sergio Giombini
    • 1
  • Angelo Nespolo
    • 1
  • Clara Milanese
    • 1
  • Andrea Salmaggi
    • 1
  1. 1.Istituto Nazionale NeurologicoMilanItaly

Personalised recommendations