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Automatic decomposition electromyography in idiopathic inflammatory myopathies

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Abstract

Automatic decomposition electromyography (ADEMG) is a commercially available software package with installed reference values that enables the objective measurement of motor unit action potentials (MUAPs). To assess the diagnostic yield of this package in idiopathic inflammatory myopathies (IIM) we performed biceps brachii ADEMG in 17 patients with polymyositis, dermatomyositis and inclusion body myositis. Results were compared with those in 12 controls, and with the results of conventional EMG of the biceps and other muscles. Decreased mean values for MUAP duration occurred significantly more frequently in IIM patients than in controls; other MUAP characteristics did not differ. In IIM patients, decreased mean amplitude and increased mean number of turns occurred significantly less frequently on ADEMG than did corresponding abnormalities on conventional biceps EMG. Decreased mean values for duration and amplitude, and increased mean values for number of turns were seen significantly less often on ADEMG than corresponding abnormalities on conventional EMG of four different, individually chosen muscles. Overall evaluation of ADEMG resulted in a diagnosis of “possible myopathy” in 1 and “probable myopathy” in 8 patients, whereas overall evaluation of conventional EMG led to a diagnosis “suggestive of IIM” in 13 patients. We conclude that, although measurement of mean MUAP duration might be valuable in IIM diagnosis, our results do not favour the use of biceps brachii ADEMG and the installed reference values for the diagnosis of IIM. We suggest modifications to improve ADEMG's applicability.

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Correspondence to Peter J. H. Jongen.

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Jongen, P.J.H., Vingerhoets, H.M., Roeleveld, K. et al. Automatic decomposition electromyography in idiopathic inflammatory myopathies. J Neurol 243, 79–85 (1996). https://doi.org/10.1007/BF00878536

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Key words

  • Electromyography
  • Automatic decomposition electromyography
  • Polymyositis
  • Dermatomyositis