Reference values for renal concentrating capacity in children by the desmopressin test
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Reference values are reported for maximal renal concentrating capacity in children using intranasally administered desmopressin. The report is based on 591 tests in 473 healthy children aged 0.5–13 years. The concentrating capacity increased markedly during the first years of life and reached a plateau at the age of 3 years. The mean value minus two standard deviations was 525 mosmol/kg at 1 year of age and 825 mosmol/kg at 3 years of age.
Key wordsRenal concentrating capacity Desmopressin
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- 2.Winberg J (1959) Determination of renal concentration capacity in infants and children without renal disease. Acta Paediatr Scand 48: 318–328Google Scholar
- 6.Bradley JV (1968) Distribution-free statistical tests. Prentice Hall, Eaglewood Cliffs, New Jersey, pp 68–86Google Scholar
- 7.Mantel N (1960) Chi-square tests with one degree of freedom. Extension of the Mantel-Haenszel procedure. J Am Stat Assoc 58: 690–700Google Scholar
- 11.Monson JP, Hocken AG (1978) Desmopressin urine concentration test. BMJ 1: 24Google Scholar
- 12.Delin K, Aurell M, Benz H (1979) Assessment of renal concentrating ability. BMJ 1: 888–889Google Scholar
- 15.Winberg J (1959) Renal function studies in infants and children with acute nonobstructive urinary tract infections. Acta Paediatr Scand 48: 577–589Google Scholar