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Journal of Neurology

, Volume 241, Issue 3, pp 153–156 | Cite as

Stroke in Fabry's disease

  • R. P. Grewal
Original Communication

Abstract

This study was performed to characterize the frequency, clinical presentation and etiology of cerebrovascular complications in patients with Fabry's disease. Thirty-three patients (age range 6–64 years) with Fabry's disease were reviewed, eight (24%) of whom suffered cerebrovascular complications. All patients developed ischemic strokes involving small arterial vessels which occurred in equal frequency in carotid and vertebrobasilar distributions. In six of these eight patients, a stroke occurred prior to age 40 years. Stroke frequently complicates Fabry's disease and represents a significant source of morbidity in patients affected with this condition; it usually involves thrombosis of small arteries affected by the disease process.

Key words

Fabry's disease Stroke 

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • R. P. Grewal
    • 1
  1. 1.NorthbrookUSA

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