Journal of Fluorescence

, Volume 3, Issue 3, pp 145–147 | Cite as

New diphenylhexatriene derivatives as fluorescent membrane probes: Partitioning properties

  • Alain Beck
  • Denis Heissler
  • Guy Duportail
Probe Development
  • 41 Downloads

Abstract

Three new diphenylhexatriene derivatives, two phospholipids and one single-chain amphiphilic molecule, have been synthesized and considered as probes for measuring membrane fluidity by fluorescence anisotropy. The possibility of using these probes to determine specifically fluidity of inner leaflets of cellular plasma membranes was inferred from their partitioning properties between gel and liquid crystalline phases of phospholipid vesicles of binary composition.

Key Words

Diphenylhexatriene derivatives partitioning properties membrane fluidity 

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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • Alain Beck
    • 1
  • Denis Heissler
    • 1
  • Guy Duportail
    • 2
  1. 1.Institute de Chimie, URA 31 CNRSUniversité Louis PasteurStrasbourgFrance
  2. 2.Centre de Recherches Pharmaceutiques, Laboratoire de Physique, URA 491 CNRSUniversité Louis PasteurStrasbourgFrance

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