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Clinical quiz

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References and further reading

  1. 1.

    Stapleton FB, Linshaw MA, Hassanein K, Gruskin AB (1978) Uric acid excretion in normal children. J Pediatr 92: 911–914

  2. 2.

    Stapleton FB, Nash DA (1983) A screening test for hyperuricosuria. J Pediatr 102: 88–90

  3. 3.

    Kelley WN, Wyngaarden JB (1983) Clinical syndromes associated with Hypoxanthine-guanine phosphoribosyl-transferase deficiency. In: Stanbury JB, Wyngaarden JB, Frederickson DS (eds) The metabolic basis of inherited disease, 5th edn. McGraw-Hill, New York, pp 1115–1144

  4. 4.

    Lorentz WB Jr, Burton BK, Trillo A, Browning MC (1984) Failure to thrive, hyperuricemia, and renal insufficiency in early infancy secondary to partial hypoxanthine-guanine phosphoribosyl transferase deficiency. J Pediatr 104: 94–97

  5. 5.

    Holland PC, Dillon MG, Pincott J, Simmonds HA, Barratt TM (1983) Hypoxanthine-guanine phosphoribosyl transferase deficiency presenting with gout and renal failure in infancy. Arch Dis Child 58: 831–833

  6. 6.

    Sweetman L, Hoch MA, Bakay B, Borden M, Lesh P, Nyhan WL (1978) A distinct human variant of hypoxanthineguanine phosphoribosyl transferase. J Pediatr 92: 385–389

  7. 7.

    Boss GR, Seegmiller JE (1979) Hyperuricemia and gout — classification, complications and management. N Engl J Med 300: 1459–1468

  8. 8.

    Wilson JM, Young AB, Kelley WN (1983) Hypoxanthine-guanine phosphoribosyl transferase deficiency — the molecular basis of the clinical syndromes. N Engl J Med 309: 900–910

  9. 9.

    McDonald JA, Kelley WN (1971) Lesch-Nyhan syndrome — altered kinetic properties of mutant enzyme. Science 171: 689–691

  10. 10.

    Wilson JM, Kelley WN (1983) Molecular basis of hypoxanthineguanine phosphoribosyl transferase deficiency in a patient with Lesch-Nyhan syndrome. J Clin Invest 71: 1331–1335

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Schoeneman, M.J. Clinical quiz. Pediatr Nephrol 4, 203–205 (1990). https://doi.org/10.1007/BF00858843

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