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The application of molecular biology to the prenatal diagnosis of renal disease

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Abstract

The rapid development of new techniques in molecular biology is leading to identification of the genes responsible for a wide variety of diseases. Several renal conditions are caused by gene defects and are amenable to this approach. The process of gene mapping is discussed and the current position regarding prenatal diagnosis and carrier testing for genetic renal disease is reviewed.

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Correspondence to Frances A. Flinter.

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Flinter, F.A., Bobrow, M. The application of molecular biology to the prenatal diagnosis of renal disease. Pediatr Nephrol 2, 343–350 (1988). https://doi.org/10.1007/BF00858691

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Key words

  • Molecular biology
  • DNA probes
  • Prenatal diagnosis
  • Carrier testing