Pediatric Nephrology

, Volume 8, Issue 5, pp 595–597

Renal cell carcinoma developing in the pediatric recipient of an adult cadaveric donor kidney

  • Rekha Agrawal
  • Maria Picken
  • Gordon J. Kinzler
  • David Hatch
  • Donald I. Moel
Brief Report

DOI: 10.1007/BF00858138

Cite this article as:
Agrawal, R., Picken, M., Kinzler, G.J. et al. Pediatr Nephrol (1994) 8: 595. doi:10.1007/BF00858138

Abstract

Renal cell carcinoma is an uncommon renal tumor in children, comprising between 1.8% and 6.3% of all malignant renal tumors of childhood (whereas renal cell carcinoma is the commonest renal tumor in adults). We describe a 15-year-old girl with chronic renal failure secondary to renal dysplasia and branchio-oto-renal syndrome, who received a cadaveric renal transplant at 8 years of age from a 25-year-old male donor. She developed severe chronic rejection 4 years after the transplant. A transplant nephrectomy was performed because of persistent gross hematuria. Histopathology of this graft showed chronic severe rejection and papillary necrosis. A fortuitous finding was a 1.5-cm renal cell carcinoma at one of the poles. We suggest that tumors which occur more commonly in adults and less commonly in children must be considered in children receiving adult organ transplants.

Key words

Renal cell carcinoma Renal transplant Pediatric recipient 

Copyright information

© IPNA 1994

Authors and Affiliations

  • Rekha Agrawal
    • 1
  • Maria Picken
    • 2
  • Gordon J. Kinzler
    • 3
  • David Hatch
    • 3
  • Donald I. Moel
    • 1
  1. 1.Division of Pediatric NephrologyLoyola University Medical CenterMaywoodUSA
  2. 2.Division of Surgical PathologyLoyola University Medical CenterMaywoodUSA
  3. 3.Division of Transplant SurgeryLoyola University Medical CenterMaywoodUSA

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