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FatalPneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis

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A 4-year-old female with nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) was treated with pulse methylprednisolone and chlorambucil therapy. She subsequently developed fatalPneumocystis carinii pneumonia (PCP). This is the first report of a pediatric patient whose treatment for FSGS resulted in PCP raising the issue of PCP prophylaxis for these patients.

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Correspondence to Jerome L. Murphy.

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The views expressed in this material are those of the authors and do not reflect the official policy or position of the United States government, the Department of Defense, or the Department of the Air Force.

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Murphy, J.L., Kano, H.L., Chenaille, P.J. et al. FatalPneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis. Pediatr Nephrol 7, 444–445 (1993). https://doi.org/10.1007/BF00857565

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Key words

  • Captopril
  • Clorambucil
  • Focal segmental glomerulosclerosis
  • Pulse methylprednisolone
  • Pneumocystis carinii pneumonia