The case of a 10.5-year-old boy who had complete right main pulmonary artery thromboembolism complicating steroid-resistant nephrotic syndrome is presented. Despite the massive nature of the lesion clinical symptoms were relatively minor. The thromboembolism was successfully treated with intrapulmonary artery streptokinase. The case highlights the discrepancy that may be found between the clinical and pathological findings in pulmonary thromboembolism in the nephrotic syndrome of childhood.
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Gootman N, Gross J, Mensch A (1964) Pulmonary artery thrombosis. A complication occurring with prednisone and chlorothiazide therapy in two nephrotic patients. Pediatrics 34: 861–868
Symchych PS, Perrin EV (1965) Thrombosis of the main pulmonary artery in nephrosis. Am J Dis Child 110: 636–642
Levin SE, Zamit R, Schmaman A (1967) Thrombosis of the pulmonary arteries and the nephrotic syndrome. Br Med J 1: 153–154
Leiberman E, Heuser E, Gilchrist GS, Donnell GN, Landing BH (1968) Thrombosis, nephrosis and corticosteroid therapy. J Pediatr 73: 320–328
Vanapruks V, Meckangvan P (1979) Thromboembolism in minimal change nephrotic syndrome. Southeast Asian J Top Med Public Health 10: 400–402
Jandra J, Zabrodsky V, Spatenka J, Tuma S (1986) Thrombosis of the inferior vena cava with successive lung embolization in a 15 year old boy with nephrotic syndrome. Pediatr Padol 21: 177–182
Egli F, Elminger P, Stalder G (1974) Thromboembolism in nephrotic syndrome. Abstract no. 42, Eur Soc Paediatr Nephrol. Pediatric Res 8: 903
Mehls O, Andrassy K, Ritz E (1984) Disseminated intravascular coagulation and platelet activation in the nephrotic syndrome. Eur J Paediatr 141: 261–266
Hoyer PF, Gonda S, Barthels M, Krohn HP, Brodehl J (1986) Thromboembolic complications in children with nephrotic syndrome. Acta Paediatr Scand 75: 804–810
Mehls O, Andrassy K, Koderisch J, Herzog U, Ritz E (1986) Hemostasis and thromboembolism in children with nephrotic syndrome: differences from adult. J Pediatr 110: 862–867
Alkjaersig N, Fletcher AP, Narayanan M, Robson AM (1987) Course and resolution of the coagulopathy in nephrotic children. Kidney Int 31: 772–780
Beaufils F, Schlegel N, Loirat C, Marotte R, Pillion G, Mathieu H (1985) Urokinase treatment of pulmonary artery thrombosis complicating the pediatric nephrotic syndrome. Crit Care Med 13: 132–134
Cecchin E, DeMarchi S, Panarello G, DeAngelis V (1987) Rheological abnormalities of erythrocyte deformability and increased glycosylation of hemoglobin in the nephrotic syndrome. Am J Nephrol 7: 18–21
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Jones, C.L., Hébert, D. Pulmonary thrombo-embolism in the nephrotic syndrome. Pediatr Nephrol 5, 56–58 (1991). https://doi.org/10.1007/BF00852846
- Nephrotic syndrome
- Pulmonary thromboembolism