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Pediatric Nephrology

, Volume 1, Issue 2, pp 145–149 | Cite as

Long-term suppression of hyperparathyroidism by phosphate binders in uremic children

  • Koichiro Tamanaha
  • Robert H. K. Mak
  • Susan P. A. Rigden
  • Charles Turner
  • Kathryn M. Start
  • George B. Haycock
  • Cyril Chantler
Original Article

Abstract

Forty-five children with stable chronic renal failure, not on dialysis, were treated conservatively with a regimen of mild dietary phosphate restriction and high-dose phosphate binders for up to 5 years. Both aluminum hydroxide and calcium carbonate were used initially, but almost all patients were taking calcium carbonate towards the end of the period. Serum immunoreactive parathyroid hormone concentrations were significantly decreased and were within the normal range after 1 year and remained normal during treatment. There was no significant change in renal function over the same treatment period. We conclude that calcium carbonate should be used as the phosphate binder of choice in the long-term suppression of hyperphosphatemia and hyperparathyroidism in uremic children.

Key words

Chronic renal failure Hyperparathyroidism Phosphate binder Aluminum hydroxide Calcium carbonate 

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Copyright information

© IPNA 1987

Authors and Affiliations

  • Koichiro Tamanaha
    • 1
  • Robert H. K. Mak
    • 1
  • Susan P. A. Rigden
    • 1
  • Charles Turner
    • 1
  • Kathryn M. Start
    • 1
  • George B. Haycock
    • 1
  • Cyril Chantler
    • 1
  1. 1.Evelina Children's Hospital, United Medical Schools of Guy's and St. Thomas HospitalsGuy's HospitalLondonUK

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