Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

The use of the method of anaphylaxis with desensitization for the study of the antigenic properties of tumors during heterotransplantation

  • 15 Accesses

Summary

The method of anaphylaxis with desensitization makes it possible to analyze the antigenic properties of the heterotransplanted tumors in guinea pigs with considerable precision. It was demonstrated that the temporary growth of the mouse tumor in an animal of another species does not alter considerably its antigenic properties. The antigens of the original tumor, particularly the antigen characterizing the species specificity of the protein are preserved in the heterotransplant of the tumor in these conditions.

This is a preview of subscription content, log in to check access.

Literature Cited

  1. [1]

    V. K. Kozlov, Biull. Eksptl. Biol. i Med. 37, 4, 56–59 (1954).

  2. [2]

    G. V. Suvorova, Biull. Eksptl. Biol. i Med. No. 1, 82–85 (1957). See English translation.

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kozlov, V.K. The use of the method of anaphylaxis with desensitization for the study of the antigenic properties of tumors during heterotransplantation. Bull Exp Biol Med 46, 1362–1367 (1958). https://doi.org/10.1007/BF00845182

Download citation

Keywords

  • Public Health
  • Temporary Growth
  • Species Specificity
  • Mouse Tumor
  • Original Tumor