Monatshefte für Chemie / Chemical Monthly

, Volume 122, Issue 12, pp 1055–1061 | Cite as

Pyridazines, LVIII: 1-Phenyl-1-pyridazinyl-2-substituted ethenes, synthesis and configuration

  • Gottfried Heinisch
  • Wolfgang Holzer
  • Thierry Huber
Organische Chemie Und Biochemie


Starting from phenyl pyridazinyl ketones1 and3 various 1-phenyl-1-pyridazinyl-2-substituted ethenes (2 a–c, 4, 5 a, b, 6 a, b, 7–9) were prepared by Wittig-Horner- oder Wittig-type reactions. Configurational assignments of these novel compounds were achieved by NOE difference spectroscopy.


Phenyl-4-pyridazinylmethanone Phenyl-3-pyridazinylmethanone Phenyl-pyridazinyl-ethenes configuration of NOE-difference spectroscopy 

Pyridazine, 58. Mitt.: Neue 2-substituierte 1-Phenyl-1-pyridazinylethene, Synthese und Konfiguration


Aus den Phenyl-pyridazinylketonen1 und3 wurden mittels Wittig-Horner- bzw. Wittig-Reaktion die 2-substituierten Phenyl-pyridazinylethene2 a–c, 4, 5 a, b, 6 a, b, 7–9 dargestellt. Die Aufklärung der Konfiguration dieser neuen Verbindungen erfolgte mittels NOE-Differenzspektroskopie.


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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • Gottfried Heinisch
    • 1
  • Wolfgang Holzer
    • 1
  • Thierry Huber
    • 1
  1. 1.Institute of Pharmaceutical ChemistryUniversity of ViennaWienAustria

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