Journal of Bioenergetics and Biomembranes

, Volume 21, Issue 5, pp 621–632

Molecular properties of the fungal plasma-membrane [H+]-ATPase

  • Robert K. Nakamoto
  • Carolyn W. Slayman

DOI: 10.1007/BF00808117

Cite this article as:
Nakamoto, R.K. & Slayman, C.W. J Bioenerg Biomembr (1989) 21: 621. doi:10.1007/BF00808117


The fungal plasma membrane contains a proton-translocating ATPase that is closely related, both structurally and functionally, to the [Na+, K+]-, [H+, K+]-, and [Ca2+]-ATPases of animal cells, the plasma-membrane [H+]-ATPase of higher plants, and several bacterial cation-transporting ATPases. This review summarizes currently available information on the molecular genetics, protein structure, and reaction cycle of the fungal enzyme. Recent efforts to dissect structure-function relationships are also discussed.

Key Words

ATPase [H+]-ATPase proton transport Neurospora crassa Saccharomyces cerevisiae Schizosaccharomyces pombe 

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Robert K. Nakamoto
    • 1
  • Carolyn W. Slayman
    • 1
    • 2
  1. 1.Department of Human GeneticsYale School of MedicineNew Haven
  2. 2.Department of Cellular and Molecular PhysiologyYale School of MedicineNew Haven

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