Bulletin of Experimental Biology and Medicine

, Volume 84, Issue 3, pp 1314–1317 | Cite as

Effect of soluble H-2 antigens on the cytotoxic effect and adsorption of immune lymphocytes

  • I. F. Kotomina
  • T. P. Pletneva
Microbiology and Immunology
Received:
  • 13 Downloads

Abstract

Serologically active preparations of soluble H-2 antigens were obtained by extraction with 3 M KCl from ascites cells of leukemia L1210 (H-2d) and sarcoma MCh-11 (H-2b). These preparations had no specific effect on the cytotoxic action of immune lymphocytes on target cells in vitro and did not inhibit adsorption of lymphocytes on a monolayer of the corresponding target cells.

Key Words

Soluble H-2 antigens cytotoxic effect T cells 
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Literature Cited

  1. 1.
    B. D. Brondz, Byull. Éksp. Biol. Med., No. 5, 64 (1964).Google Scholar
  2. 2.
    B. D. Brondz, Folia Biol. (Prague),14, 115 (1968).Google Scholar
  3. 3.
    B. D. Brondz and A. E. Snegireva, Immunology,20, 457 (1971).Google Scholar
  4. 4.
    B. D. Brondz, I. E. Egorov, and G. I. Drizlikh, J. Exp. Med.,141, 11 (1975).Google Scholar
  5. 5.
    G. I. Drizlikh and B. D. Brondz, Molekul. Biol., No. 2, 253 (1977).Google Scholar
  6. 6.
    G. I. Drizlikh, A. V. Andreev, I. F. Kotomina, et al., Byull. Éksp. Biol. Med., No. 3, 340 (1976).Google Scholar
  7. 7.
    A. Basten, J. F. A. P. Miller, and R. Abraham, J. Exp. Med.,141, 547 (1975).Google Scholar
  8. 8.
    B. Benacerraf and H. O. McDevitt, Science,175, 273 (1972).Google Scholar
  9. 9.
    G. Berke, K. Sullivan, and B. Amos, J. Exp. Med.,135, 1334 (1972).Google Scholar
  10. 10.
    U. Binz and H. Wigzell, Scand. J. Immunol.,5, 359 (1976).Google Scholar
  11. 11.
    B. Bonavida, J. Immunol.,112, 926 (1974).Google Scholar
  12. 12.
    M. Braun, Cell. Immunol.,25, 1 (1976).Google Scholar
  13. 13.
    R. E. Cone, J. Immunol.,116, 847 (1976).Google Scholar
  14. 14.
    P. A. Gorer and P. O'Gorman, Transplant. Bull.,3, 142 (1956).Google Scholar
  15. 15.
    D. Götze and R. Reisfeld, J. Immunol.,112, 1643 (1974).Google Scholar
  16. 16.
    R. A. Reisfeld, M. A. Pellegrino, and B. D. Kahan, Science,172, 1194 (1971).Google Scholar
  17. 17.
    R. D. Stulting, R. F. Todd, and L. R. Gooding, Transplantation,21, 71 (1976).Google Scholar
  18. 18.
    R. F. Todd and G. Berke, Immunochemistry,11, 313 (1974).Google Scholar
  19. 19.
    R. F. Todd, R. D. Stulting, and D. B. Amos, Cell. Immunol.,18, 304 (1975).Google Scholar
  20. 20.
    H. Wagner and W. Boyle, Nature (London) New Biol.,240, 92 (1972).Google Scholar

Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • I. F. Kotomina
  • T. P. Pletneva

There are no affiliations available

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