Pediatric Cardiology

, Volume 16, Issue 3, pp 145–146 | Cite as

Diastolic runoff with widened arterial pulse pressure in an adolescent with widely metastatic testicular chriocarcinoma

  • J. C. Murray
  • D. Oshman
  • C. P. Steuber
Case Reports

Abstract

Widened arterial pulse pressure is often found with conditions having exaggerated diastolic runoff flow, such as aortic insufficiency and arteriovenous malformation. We report a 17-year-old boy with metastatic testicular choriocarcinoma and a widened pulse pressure. Ultrasonography and Doppler analysis revealed significant runoff flow into multiple large hepatic metastases. After chemotherapy, there was diminution in his metastases, a narrowing of the pulse pressure, and no evidence of runoff flow in the liver. These cardiovascular findings have not been previously described in association with metastatic vascular malignancies.

Key words

Choriocarcinoma Pulse pressure 

References

  1. 1.
    Ablin A, Isaacs H (1993) Germ cell tumors. In:Principles and Practice of Pediatric Oncology. Lippincott, Philadelphia, pp 867–887Google Scholar
  2. 2.
    Braunwald E (1991) Disorders of the cardiovascular system. In: Wilson JD, Braunwald E, Isselbacher KJ, et al (eds)Harrison's Principles of Internal Medicine. McGraw-Hill, New York, pp 948–951Google Scholar
  3. 3.
    El-Said GM, El-Refaee MM (1990) Rheumatic heart disease. In: Garson A, Bricker JT, McNamara DG (eds)The Science and Practice of Pediatric Cardiology. Lea & Febiger, Malvern, PA, pp 1512–1518Google Scholar
  4. 4.
    Green JF (1982) Determinants of arterial blood pressure and its normal value. In:Fundamental Cardiovascular and Pulmonary Physiology: An Integrated Approach for Medicine, Lea & Febiger, Philadelphia, pp 127–135Google Scholar
  5. 5.
    Levinson GE (1969) Valvular heart disease. In: Gordon BL, Carleton RA, Faber LP (eds)Clinical Cardiopulmonary Physiology. Grune & Stratton, Orlando, FL, pp 248–250Google Scholar

Copyright information

© Springer-Verlag New York Inc 1995

Authors and Affiliations

  • J. C. Murray
    • 1
  • D. Oshman
    • 2
  • C. P. Steuber
    • 1
  1. 1.Section of Hematology-Oncology, Department of PediatricsBaylor College of Medicine and Texas Children's HospitalHoustonUSA
  2. 2.Department of RadiologyBaylor College of Medicine and Texas Children's HospitalHoustonUSA

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